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Written by:  Dr Tom Shurlock for and on behalf of GWF Nutrition Limited.

Copyright GWF Nutrition Limited August 2016 - Not for reproduction.

It’s thought that 25-50% of foals and 60-90% of performance horses have ulcers. It is likely, due to the probably causes of ulceration, that many leisure horses also suffer from the condition. In its worst case ulceration can also occur in the horse’s gullet and further down the intestine from the stomach, and may be differentiated, clinically by vets, under different names. But they all have a common starting point and this involves disruption of the normal function of the stomach.

The horse’s stomach constantly produces hydrochloric acid (HCl) from specialised cells. This is an extremely aggressive acid and is prevented from burning the stomach wall by a thick layer of mucus produced by goblet cells. These are both situated in the lower portion of the stomach. The role of acid in the stomach is to provide an environment for the pre-digestion of nutrients,  as well as stimulating enzyme release into the small intestine when the stomach contents released. As the stomach of the horse is small this, also, is a continuous process.

In the case of stomach ulcers the traditional theory is that acid secretion, coupled with disruptions in mucus production, mainly stress related, led to lesions that were exacerbated by contact with acid.

We now know that the acidity of the stomach encourages some bacteria that ferment starch to lactic acid which makes the stomach environment even more acidic, and this encourages aggressive bacteria like heliobacter.

Lactic acid has been demonstrated to be able to penetrate the mucosal cells and this is thought to be another route for generating lesions (Figure 1). Additionally once a lesion has been created it becomes quickly infected with the bacteria (in red) that, although as yet unidentified, are thought to produce the lactic acid (Figure 2). Heliobacter, which are the primary culprit in human ulcers have been detected in horse’s stomachs.

Figure 1 Arrowed – Ulcer

Figure 2 Arrowed - Infection

As with any microbial system once the balance has been shifted it tends to reinforce itself. Therefore an increase of these lactic producers would be expected and these will escape into the intestine, creating their own micro-environment through lactic acid production and likely causing lesions along the small intestine. Although gastric ulcers grab the headlines in horses, ulceration along the whole small intestine are not uncommon.

Having previously quoted that the majority of domestic sources have, or may have, ulcers one significant statistic shows up. Horses on permanent pasture have a much lower incidence, and this fact provides the clue on what is happening.

In the natural state the horse grazes continuously. This means it is constantly chewing, producing saliva which is forced into the food and swallowed. The saliva contains sodium bicarbonate to help neutralise the stomach acid. and the forage has an intrinsic ability to bind up some of the acid (Acid Binding Capacity). Between them they maintain the stomach at reasonable acidity level somewhat akin to vinegar compared to the battery acid strength of the secreted HCl. At these levels the acid producing bacteria are suppressed. Even when stressed (being hunted, fighting during mating) these factors are short-lived and relatively infrequent.

In the case of the domesticated horse several factors are now introduced that disrupt normal function.

Firstly, stress: Not necessarily what we would regard as stress, but an environment the horse finds itself in that does not encompass normal behavioural activity: Stabling, transport, unfamiliar surroundings and the more familiar stresses of disease, injury or pain. Of course we minimise this as far as we are able but some factors are unavoidable. The result of these stresses, whether intermittent (transport) or long term (being at the bottom – or top – of a social group) can be disruption of the production of mucus to line the stomach causing a breach in the defence against acid burns.

Secondly, exercise: A wild horse will run if the stimulus is there and it will run on a “full stomach”. Performance horses tend to run on an empty stomach and so there is no saliva or forage to mop up the acid. Hard exercise constricts the stomach and pushes the acid up into the upper section that has little mucosal protection against acid burns. It is little wonder that up to 90% of racehorses suffer from ulcers.

Thirdly, feeding: Constant feeding is not always an option. Even with a full hay net the introduction of “meals”, whether as hard feed or as cereals/proteins, will have an effect on stomach physiology and feeding behaviour. Removal of feed during stress periods will also have an impact. There will be periods where acid production has little or nothing to act on, or encourages microbial breakdown of high starch feeds releasing factors which promote the potential for ulcers.

So if we have a horse that is not constantly grazing, and experiences one or many of the above factors, there is a possibility that is will be prone to ulcers. So what can we do to help?

Obviously there are husbandry methods we can use. Maintaining routine, avoiding obvious stresses whenever possible and treating injury are all positive actions. However we need to think about feeding as well. So how do we protect the stomach, gullet and intestine from the actions of penetrating acids and infections?

 

1 - Water. For every litre a horse drinks four litres are produced by the saliva and gastric secretions and later re-absorbed. If water is restricted, especially when eating dry feed, saliva may be compromised and saliva contains bicarbonate that helps neutralise the stomach’s acid environmen.                        

                       

2 - Reduce starchy materials. Starch is an excellent provider of energy and is convenient to feed, but overfeeding is associated with many disorders. In the stomach starch has a relatively low Acid Binding Capacity (ABC), is not good at soaking up stomach acid, and will act as “fuel” for those bacteria that thrive in more acidic conditions.

 

3 - Introduce feeds with a high ABC such as legume hays and soluble fibres. For example, at an acid level of pH4, the level that a normally functioning stomach should be, and at pH 3, which is in the “problem” region:

4 - Protect the mucosal lining. Although there are proprietary brands available, one of the most widely reported nutrients that can help is pectin. In acidic conditions pectin alters its structure to one that is similar to mucus and it has been shown to bind to, and thicken, the stomach mucosa. In the presence of surfactants (naturally occurring products that emulsify oils and water) the effect is enhanced.​

So, ideally, a feed that contains legumes, pectins and surfactants, and which can be fed as a wet feed would be the best possible complementary feed for forage. It would also have to have low levels of starch but provide sufficient energy to replace cereals or hard feed and reduce the overall starch load.

 

GWF Nutrition feeds are formulated with this in mind:

Equilibra 500 contains ingredients that have high ABC and also provides appreciable quantities of pectins. Coupled with oat phospholipids, which act as emulsifiers, the potential for mucus support is present.

 

Alfalfa Soya Oil. Research has shown that the acid binding of alfalfa can help modulate stomach acidity for up to 6 hours, enough to protect between meals.

 

Fibregest. With hempseed meal and beet pulp, products both having high ABC, using FibreGest as a forage extender will help soak up stomach acids.

 

Tiger Oats. As a lower starch, high fibre, high energy product and containing good levels of pectins and phospholipids, Tiger Oats have a good ABC value and may help mucus reinforcement.

+44 (0)1225 708482

info@gwfnutrition.com

Ulceration of the Horse's Gastro-Intestinal Tract

August 2016

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Complies with the Universal Feed Assurance Scheme - Compound Feed Code of Practice.  Registration no.: 81.  Registered in England no. 01042610  Establishment no. GB330E368.  GWF Nutrition, GWF Nutrition.com, Equilibra, The Aid Range, Oatinol and Age-ility are Registered Trade Marks ® of GWF Nutrition Limited.